Caroline Dive Selected Research

AEG 35156

4/2011	Down-regulation of XIAP by AEG35156 in paediatric tumour cells induces apoptosis and sensitises cells to cytotoxic agents.
4/2009	Phase I trial of AEG35156 administered as a 7-day and 3-day continuous intravenous infusion in patients with advanced refractory cancer.

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Caroline Dive Research Topics

Disease

88	Neoplasms (Cancer) 01/2022 - 06/2003
20	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 11/2021 - 08/2008
19	Circulating Neoplastic Cells 01/2022 - 04/2009
15	Colorectal Neoplasms (Colorectal Cancer) 04/2021 - 04/2007
11	Lung Neoplasms (Lung Cancer) 01/2019 - 04/2007
11	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/2017 - 04/2009
10	Disease Progression 11/2021 - 06/2012
10	Neoplasm Metastasis (Metastasis) 04/2021 - 07/2010
9	Hypoxia (Hypoxemia) 01/2018 - 04/2004
8	Melanoma (Melanoma, Malignant) 02/2019 - 04/2008
7	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 09/2010
6	Colonic Neoplasms (Colon Cancer) 10/2012 - 04/2004
5	Carcinogenesis 01/2019 - 09/2007
4	Breast Neoplasms (Breast Cancer) 01/2022 - 04/2008
3	Carcinoma (Carcinomatosis) 11/2020 - 12/2011
3	Neuroblastoma 01/2013 - 09/2006
3	Thrombocytopenia (Thrombopenia) 06/2012 - 04/2009
3	Obesity 03/2011 - 02/2008
2	Ovarian Epithelial Carcinoma 01/2020 - 09/2010
2	Pancreatic Neoplasms (Pancreatic Cancer) 12/2019 - 02/2016
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2019 - 11/2015
2	Biliary Tract Neoplasms (Biliary Tract Cancer) 01/2018 - 08/2015
2	Lymphoma (Lymphomas) 04/2016 - 04/2009
2	Hypertension (High Blood Pressure) 11/2015 - 08/2015
2	Fatigue 11/2015 - 08/2015
2	Glioma (Gliomas) 05/2014 - 05/2013
2	Rhabdomyosarcoma 01/2013 - 04/2011
2	Ewing Sarcoma (Sarcoma, Ewing) 01/2013 - 04/2011
2	Osteosarcoma (Osteogenic Sarcoma) 01/2013 - 04/2011
1	COVID-19 01/2022
1	Adenocarcinoma of Lung 10/2021

Drug/Important Bio-Agent (IBA)

44	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2008
20	Pharmaceutical PreparationsIBA 10/2018 - 06/2003
14	Proteins (Proteins, Gene)FDA Link 04/2021 - 04/2004
11	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 01/2007
8	Biological ProductsIBA 01/2022 - 01/2007
8	Cell-Free Nucleic AcidsIBA 11/2020 - 01/2008
7	Etoposide (VP 16)FDA LinkGeneric 11/2021 - 09/2006
6	Circulating Tumor DNAIBA 01/2022 - 08/2008
6	Cisplatin (Platino)FDA LinkGeneric 08/2015 - 09/2006
6	Oxygen (Dioxygen)IBA 05/2014 - 04/2004
5	PlatinumIBA 11/2021 - 09/2010
5	ABT-737IBA 01/2016 - 11/2008
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 04/2021 - 10/2004
4	Doxycycline (Periostat)FDA LinkGeneric 02/2019 - 04/2005
4	cediranib (AZD2171)IBA 01/2019 - 08/2015
4	Phosphotransferases (Kinase)IBA 10/2018 - 10/2004
4	AntigensIBA 02/2014 - 03/2008
4	Phosphatidylinositols (Phosphatidylinositol)IBA 02/2014 - 06/2009
4	Peptides (Polypeptides)IBA 06/2012 - 04/2008
4	CaspasesIBA 03/2012 - 04/2007
3	Carboplatin (JM8)FDA LinkGeneric 01/2019 - 11/2015
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2019 - 11/2015
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 08/2015
3	Bevacizumab (Avastin)FDA Link 11/2018 - 09/2014
3	navitoclaxIBA 01/2016 - 03/2011
3	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2014 - 04/2011
2	C-Reactive ProteinIBA 01/2022 - 01/2017
2	Estrogen ReceptorsIBA 01/2022 - 12/2018
2	AZD9496IBA 01/2022 - 12/2018
2	ProteomeIBA 01/2022 - 01/2019
2	EpitopesIBA 01/2020 - 01/2016
2	Caspase 3 (Caspase-3)IBA 02/2019 - 11/2008
2	Keratin-18 (Keratin 18)IBA 01/2018 - 11/2008
2	NF-kappa B (NF-kB)IBA 11/2017 - 02/2008
2	plasma protein Z (protein Z)IBA 01/2017 - 06/2016
2	RNA (Ribonucleic Acid)IBA 01/2017 - 12/2014
2	Protein Isoforms (Isoforms)IBA 01/2016 - 07/2005
2	Tyrosine Kinase InhibitorsIBA 11/2015 - 06/2010
2	AZD3965IBA 05/2015 - 02/2014
2	PI103IBA 01/2013 - 06/2010
2	Small Interfering RNA (siRNA)IBA 01/2013 - 09/2006
2	big gastrinIBA 06/2012 - 03/2011
2	EnzymesIBA 03/2012 - 04/2009
2	Cytotoxins (Cytolysins)IBA 12/2011 - 09/2010
2	Insulin-Like PeptidesIBA 04/2011 - 02/2008
2	AEG 35156IBA 04/2011 - 04/2009
2	Vincristine (Oncovin)FDA LinkGeneric 04/2011 - 09/2006
2	Hypoxia-Inducible Factor 1IBA 03/2011 - 04/2004
2	BH 3IBA 03/2011 - 11/2008
2	ErbB Receptors (EGF Receptor)IBA 11/2010 - 06/2010
2	src-Family KinasesIBA 07/2010 - 10/2004
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 04/2010 - 04/2008
2	Messenger RNA (mRNA)IBA 04/2009 - 04/2004
1	AlbuminsIBA 01/2022
1	Soluble Guanylyl CyclaseIBA 11/2021
1	Monomeric GTP-Binding ProteinsIBA 11/2021
1	Fluorouracil (Carac)FDA LinkGeneric 04/2021
1	Capecitabine (Xeloda)FDA Link 04/2021
1	erythromycin propionate-N-acetylcysteinateIBA 04/2021
1	LipidsIBA 11/2020
1	fosbretabulin (combretastatin A4)IBA 01/2020
1	pazopanib FDA Link 01/2020

Therapy/Procedure

36	Therapeutics 01/2022 - 06/2006
26	Drug Therapy (Chemotherapy) 11/2021 - 06/2003
7	Precision Medicine 01/2022 - 07/2014
6	Radiotherapy 01/2018 - 04/2004
2	Immunotherapy 03/2016 - 01/2016
2	Aftercare (After-Treatment) 12/2013 - 11/2008
1	Cytoreduction Surgical Procedures 01/2021